Variety gives us an exclusive first look at Drew from her new film Miss You Already.

LONDON — Variety has been given the trade exclusive on the first image from “Miss You Already,” which stars Drew Barrymore and Toni Collette. Catherine Hardwicke’s relationship drama started lensing in the U.K. earlier this month.

Collette and Barrymore play Milly and Jess, who have been best friends since childhood. Their friendship is put to the test as Jess struggles to have a much longed-for baby and Milly finds out she has breast cancer.

Pic also stars Dominic Cooper (“The Devil’s Double”) and Paddy Considine (“Pride”) as the men in their lives, and Jacqueline Bisset rounds out the stellar cast as Collette’s mother.

Hardwicke (“Twilight,” “Thirteen”) directs from a screenplay by British writer and actor Morwenna Banks (“Damned,” “The Announcement”).

Principal photography started on Sept. 7, with shooting largely focused on London, and later moving to the Yorkshire Moors, England.

“I was trained as an architect and London is flat out inspiring. We’re showing a different side of the city — the collision of old and new that you find on every corner,” Hardwicke said.

“To help me pre-visualize the scenes everyone on the crew from the art department to the location managers have acted out the parts of midwives, pregnant women giving birth, and even sheep up in Yorkshire. With a cast that have taken over their roles with ferocity and their special brand of British wit, this film is coming alive.”

Pic, which is produced by Christopher Simon and Felix Vossen of Embargo Films, will be distributed in the U.K. by eOne, and is slated for release in October 2015. International sales are being handled by The Salt Company, which shares North American sales duties with CAA.