As a mom to two young daughters, Drew Barrymore doesn’t have a ton of time right now to be acting in films. Unless you can make her cry.

Barrymore and Toni Collette (United States of Tara) star in Miss You Already, a heartstring-plucking drama about lifelong friends Jess (Barrymore) and Milly (Collette) coping with Milly’s breast cancer. It premiered Saturday at the Toronto International Film Festival and opens wide on Nov. 6

When Barrymore’s agent insisted she read the script, she did so while holding then-newborn daughter Frankie in her arms and trying to feed toddler Olive breakfast.

“I was trying to hide my tears from my daughter because I didn’t want to scare her,” said Barrymore, who was so taken with the story that she couldn’t say no.

While she likely won’t be pouring drinks at homey dive bar Sweaty Betty’s on this visit to Toronto – as she famously did in 2009, during the wrap party for her movie Whip It – Barrymore loves the Toronto International Film Festival vibe.

“It just has a focus that’s the greatest place to show movies,” Barrymore said. “It’s twofold – the audiences are extraordinary, and the festival is like the most important festival on a business level. I mean, if you get into Toronto, it’s a serious deal.”

With Barrymore balancing parenting, film production and her successful cosmetics company, time is perhaps her most precious commodity. But she realizes that if there’s going to be another Charlie’s Angels movie – Barrymore starred in and produced the 2000 and 2003 instalments – time is running out.

“I’m like, ‘We’d better do this before we’re all in wheelchair,’ because that’s more of like the Naked Gun version,” Barrymore said. “Everyone’s life is in a very distinct place, and movies are not the universe of a bunch of people who were involved in making the first two. So it’s tricky, but we talk about it very seriously.”

But despite any rumours you may have heard, one thing that’s never going to happen is a sequel to 1982’s E.T.: The Extra-Terrestrial, the Steven Spielberg classic that made seven-year-old Drew Barrymore a household name.

“He does not ever want to make a sequel to that,” Barrymore said of her friend and godfather, Spielberg. “He didn’t at the time, and he doesn’t now. That would be really weird.”

(Source)